Description
Sandostatin LAR (Octreotide) Injection – Uses, Dosage & Benefits
Sandostatin LAR (Octreotide) Injection is a long-acting medication widely used in the treatment of acromegaly and certain gastrointestinal (GI) tumors. Manufactured by Novartis, it is available in 10mg, 20mg, and 30mg strengths for intramuscular use.
What is Sandostatin LAR Used For?
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Acromegaly Treatment: Controls excessive growth hormone production, reducing symptoms like enlarged hands and feet, coarsened facial features, sweating, and fatigue.
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Neuroendocrine & GI Tumors: Effective in managing symptoms of carcinoid tumors and VIPoma (Vasoactive Intestinal Peptide Tumors) that cause flushing, severe diarrhea, and abdominal discomfort.
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Tumor Growth Control: Helps slow the growth of certain hormone-secreting tumors.
How Sandostatin LAR Works
Sandostatin LAR contains Octreotide, a synthetic analogue of the natural hormone somatostatin. It works by:
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Inhibiting excess growth hormone secretion
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Reducing insulin and glucagon release
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Controlling hormone production from tumors
This targeted action helps relieve symptoms and maintain better disease control.
Recommended Dosage
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Starting Dose: 20mg intramuscular injection every 4 weeks.
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Adjustment: After 2 months, the dose may be decreased to 10mg or increased to 30mg every 4 weeks, depending on response and symptom control.
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Always administered by a trained healthcare professional.
Benefits of Sandostatin LAR
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Long-acting symptom control with once-monthly injections.
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Improves quality of life for patients with acromegaly and GI tumors.
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Reduces risk of complications linked to excess hormone secretion.
Possible Side Effects
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Common: Injection site pain, nausea, diarrhea, abdominal cramps, constipation.
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Serious (less common): Gallstones, thyroid imbalance, slow heart rate, changes in blood sugar.
👉 Patients should be regularly monitored by a healthcare provider.
Storage Instructions
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Store between 2°C – 8°C (refrigerated).
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Do not freeze; protect from direct light.
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Keep out of reach of children.



Ramiz Raja –
Sandostatin is really good