Description

Methycobal Injection 500mcg (10 Ampoules) – Imported from Japan by Eisai

Methycobal Injection contains Mecobalamin (Methylcobalamin), the most active and bioavailable form of Vitamin B12. It is widely used to treat Vitamin B12 deficiency, megaloblastic anemia, and peripheral neuropathy. Unlike traditional oral supplements, Methycobal injection ensures faster absorption, making it especially effective for patients with absorption issues or severe deficiency.

Key Features of Methycobal Injection

• Active Ingredient: Mecobalamin (Vitamin B12) – 500mcg per ampoule

• Pack Size: 10 ampoules (10 injections) per box

• Manufacturer: Eisai Co. Ltd., Japan (Imported)

• Form: Clear red injectable solution (pH 5.3–7.3)

• Administration: Intramuscular or subcutaneous injection

Medical Uses & Benefits

Methycobal Injection is prescribed for multiple neurological and hematological conditions, including:

• ✅ Vitamin B12 Deficiency – prevents fatigue, weakness, and anemia

• ✅ Megaloblastic Anemia – supports red blood cell production

• ✅ Peripheral & Diabetic Neuropathy – reduces numbness, tingling, and nerve pain

• ✅ Nerve Protection & Repair – promotes myelin sheath regeneration

• ✅ Cognitive & Metabolic Support – aids DNA synthesis and healthy nerve signaling

Advantages Over Oral Vitamin B12 Supplements

• 💉 Higher Absorption Rate – bypasses digestive tract issues

• ⚡ Faster Onset of Action – effective relief for nerve pain & fatigue

• 👩‍⚕️ Effective in Malabsorption Cases – suitable for patients post-GI surgery

• ✅ Better Compliance – weekly dosing vs. daily oral supplements

Recommended Dosage

• Neuropathy: 1–3 ampoules (500 mcg) per week, divided into 3 doses

• Anemia: 1 ampoule (500 mcg) 3 times weekly, followed by maintenance dosing (1–3 times monthly)

• Maintenance Therapy: As prescribed by physician

⚠️ Always use under medical supervision. Dosage may vary depending on patient condition and severity.

Mechanism of Action – How Methycobal Works

Methylcobalamin acts as a cofactor for key enzymes involved in:

1. DNA & Cell Growth: Converts homocysteine to methionine for DNA synthesis.

2. Energy & Metabolism: Facilitates conversion of methylmalonyl CoA to succinyl CoA for energy production.

3. Nerve Function: Maintains the myelin sheath for healthy nerve signaling.

4. Blood Formation: Supports red blood cell production to prevent anemia.

Side Effects & Precautions

Possible side effects (generally mild): nausea, diarrhea, rash, dizziness, or injection site irritation.

Use with caution if:

• You have Leber’s disease (hereditary optic nerve atrophy)

• You recently underwent gastrointestinal surgery

• You are taking medications that interfere with B12 absorption

Storage Instructions

• Store at room temperature, away from direct light

• Do not freeze

• Use immediately after opening ampoule