Description

Kayexalate (Sodium Polystyrene Sulfonate) Powder 454g – Imported

Kayexalate (sodium polystyrene sulfonate) is a prescription medication used to treat hyperkalemia (high potassium levels in the blood). It works as a potassium-binding resin, helping the body remove excess potassium through the stool, thereby lowering dangerously high potassium levels.

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Key Features

• Active Ingredient: Sodium Polystyrene Sulfonate

• Form: Light brown to cream powder, supplied in 454g jars

• Primary Use: Treatment of high blood potassium (hyperkalemia) in patients with kidney disease or other medical conditions

• Mechanism of Action: Exchanges sodium ions for potassium ions in the intestine, promoting fecal potassium excretion

• Storage: Keep at 15–30°C (59–86°F) in a dry place

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Indications

Kayexalate is used for:

• Treating hyperkalemia in adults and children

• Managing elevated potassium levels associated with chronic kidney disease

• Emergency reduction of high serum potassium levels under medical supervision

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Dosage & Administration

Oral Use:

• 15–60 g per day, divided into 1–4 doses

• Each dose: 15 g (approx. 4 teaspoons) mixed with water or syrup and taken immediately

Rectal Use (Enema):

• 30–50 g every 6 hours after a cleansing enema

• Should be retained as long as possible before flushing

⚠️ Dosage must always be determined by a healthcare professional depending on potassium levels and patient condition.

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Safety Information

• Common Side Effects: Constipation, diarrhea, nausea, vomiting, electrolyte disturbances (low calcium, low magnesium, hypokalemia)

• Serious Risks: Rare cases of intestinal necrosis, especially with sorbitol co-administration

• Precautions:

  • Avoid potassium-rich foods (bananas, citrus, tomatoes, potatoes, beans, nuts)

  • Do not mix with fruit juices high in potassium

  • Avoid magnesium-containing laxatives and aluminum/magnesium-based antacids

  • Maintain a fiber-rich diet to reduce constipation risk

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Drug Interactions

• May bind to other oral medications (e.g., digoxin, lithium, thyroxine), reducing absorption.

• Take other medicines at least 3 hours before or after Kayexalate (6 hours in patients with slow digestion).

• Avoid use with sorbitol due to risk of intestinal necrosis.

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Pediatric & Special Populations

• Children/Neonates: Should be used with caution; oral use is not recommended in neonates due to risk of intestinal impaction.

• Elderly/Patients with Sodium Restriction: Monitor for fluid overload and electrolyte disturbances.

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Why Choose Kayexalate?

• Proven effectiveness in lowering dangerous potassium levels

• Widely used in renal care and emergency hyperkalemia management

• Imported and supplied in 454g powder jars for flexible dosing