Description

Sandimmun Neoral 100mg 50’ct (Cyclosporine) – Uses, Benefits & Side Effects

Sandimmun Neoral 100mg is an imported prescription medicine containing cyclosporine, a powerful immunosuppressant used to prevent organ rejection and manage certain autoimmune diseases. Manufactured by Novartis, it comes in 100mg capsule strength with 50 capsules per pack, providing a reliable 1–2 month supply depending on dosing requirements.

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What is Sandimmun Neoral 100mg?

Sandimmun Neoral is a microemulsion formulation of cyclosporine, offering better absorption and bioavailability compared to the original Sandimmun. It has been trusted for over 30 years in clinical practice and extensively studied in transplant medicine and autoimmune conditions.

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Key Medical Uses of Sandimmun Neoral 100mg

Sandimmun Neoral is prescribed for:

• Organ Transplants – Prevents rejection in kidney, liver, and heart transplant patients.

• Rheumatoid Arthritis – Reduces inflammation in severe, treatment-resistant cases.

• Psoriasis – Controls moderate to severe plaque psoriasis when other therapies fail.

• Other Autoimmune Conditions (off-label) – Crohn’s disease, nephrotic syndrome, eczema, ulcerative colitis, and uveitis.

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How Sandimmun Neoral Works

The active ingredient Cyclosporine works by:

1. Binding to cyclophilin proteins inside T-cells.

2. Blocking the enzyme calcineurin, which normally triggers the release of interleukin-2 (IL-2).

3. Suppressing T-cell activation and immune response.

➡ This mechanism prevents organ rejection and reduces autoimmune-driven inflammation.

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Dosage & Administration

Dosage depends on condition, body weight, and therapeutic monitoring:

• Transplant Patients (Adults):

  • Initial dose: 15 mg/kg/day, divided into two doses.

  • Maintenance dose: 5–10 mg/kg/day (based on blood levels).

• Rheumatoid Arthritis & Psoriasis:

  • Starting dose: 1.25 mg/kg twice daily.

  • Can be increased up to 4 mg/kg/day if needed.

Always follow your doctor’s prescription and regular blood test monitoring.

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Side Effects of Sandimmun Neoral

Like all immunosuppressants, cyclosporine may cause side effects. Common ones include:

• Kidney problems (nephrotoxicity)

• High blood pressure

• Tremors

• Increased risk of infections

• Higher risk of certain cancers with long-term use

Patients require close monitoring with routine blood tests.

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Storage Instructions

• Store at 15–30°C, away from heat, moisture, and direct sunlight.

• Keep in original packaging, tightly closed.

• Shelf life: 2–3 years when stored properly.

• Keep out of reach of children.

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Why Choose Sandimmun Neoral 100mg?

• Proven efficacy in transplant medicine and autoimmune conditions.

• Microemulsion technology for consistent absorption.

• Convenient 100mg capsule for easier dosing.

• Extensively studied with over 30 years of clinical use.

• Comprehensive patient support provided by Novartis.

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Patient Reviews

✔️ “I’ve been on Sandimmun Neoral for 5 years after a kidney transplant – it has kept my organ safe with minimal side effects.”
✔️ “This medicine completely changed my psoriasis management when nothing else worked.”
✔️ “The microemulsion formula gives me more stable results compared to the older Sandimmun.”