Description

Votrient 200mg Tablets (30 Count) – Pazopanib for Advanced Kidney Cancer & Soft Tissue Sarcoma

Votrient 200mg (Pazopanib) is a prescription cancer medication used in the treatment of advanced renal cell carcinoma (kidney cancer) and certain types of advanced soft tissue sarcoma in adults. Manufactured by Novartis, this targeted therapy helps slow cancer progression by blocking tumor growth and inhibiting blood vessel formation.

---

Key Features of Votrient 200mg

• Active Ingredient: Pazopanib hydrochloride equivalent to 200mg pazopanib

• Mechanism of Action: Multi-tyrosine kinase inhibitor targeting VEGFR, PDGFR, FGFR, and c-Kit

• Indications:

  • Advanced renal cell carcinoma (kidney cancer)

  • Advanced soft tissue sarcoma in adults

• Pack Size: Available in 30-tablet and 90-tablet bottles

• Dosage: Recommended 800mg daily (four 200mg tablets) taken orally without food

---

How Votrient Works

Votrient (pazopanib) is a multi-targeted receptor tyrosine kinase inhibitor (TKI). It works by:

• Inhibiting VEGFR-1, VEGFR-2, VEGFR-3 → Blocks new blood vessel formation (angiogenesis) that feeds tumor growth

• Blocking PDGFR-α and PDGFR-β → Slows cancer cell growth and division

• Targeting FGFR and c-Kit → Reduces tumor cell proliferation

This combined mechanism helps slow the spread and progression of cancerous tumors.

---

Dosage & Administration

• Standard dose: 800mg once daily (4 tablets of 200mg each)

• Tablets must be taken on an empty stomach

  • At least 1 hour before or 2 hours after a meal

• Do not exceed 800mg daily

• Dose adjustments may be required in patients with liver impairment or those on interacting medications

---

Safety Warnings & Precautions

• ⚠️ Liver Damage Risk: Votrient can cause severe liver problems, including liver failure. Regular liver function tests are mandatory.

• ❌ Avoid Grapefruit & Grapefruit Juice: Increases drug levels and side effects.

• ❌ Avoid Alcohol: Consult your doctor before drinking alcohol during treatment.

• 🚫 Not for Pregnant or Breastfeeding Women: May harm the baby.

• ⚠️ Heart, Lung, and Liver Disease: Use with caution and under strict medical supervision.

• 🚸 Not for Children Under 18: Safety and effectiveness not established.

---

Side Effects of Votrient 200mg

Common side effects:

• Nausea, vomiting, diarrhea

• Fatigue, headache, dizziness

• Stomach pain, loss of appetite

• High blood pressure

Serious side effects (require immediate medical attention):

• Severe liver damage

• Heart rhythm changes

• Blood clots or bleeding problems

---

Monitoring During Treatment

Patients taking Votrient must undergo regular medical monitoring, including:

• Liver, kidney, and heart function tests

• Blood pressure checks

• Complete blood count (CBC)

• ECG and other assessments if needed

---

Storage & Handling

• Store at room temperature away from heat, moisture, and direct sunlight

• Keep out of reach of children

• Dispose of unused tablets safely

---

Why Choose Votrient 200mg?

• Clinically proven treatment for advanced kidney cancer and soft tissue sarcoma

• Targeted therapy that slows tumor growth and angiogenesis

• Backed by Novartis, a trusted global pharmaceutical company