Description

GNC Niacin 500mg in Pakistan – Price, Benefits, Uses, Dosage & Side Effects

GNC Niacin 500mg is a high-quality dietary supplement that provides 500 mg of niacin (vitamin B3) per vegetarian tablet. Imported from the USA, this supplement is designed to support a healthy blood lipid profile, energy metabolism, and blood vessel health.

✅ Pack Size: 100 vegetarian tablets
✅ Non-GMO & Gluten-Free
✅ Price in Pakistan: Varies by retailer (imported product)

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Key Benefits of GNC Niacin 500mg

• Supports Blood Lipid Profile: Helps reduce LDL (bad cholesterol) and triglycerides while increasing HDL (good cholesterol).

• Energy Metabolism: Niacin plays a vital role in converting food into energy for daily performance.

• Blood Vessel Health: Promotes better circulation, supports healthy blood flow, and helps protect arteries.

• Cholesterol Support: Clinically shown to raise HDL-C levels more effectively than many other supplements.

• Antioxidant Protection: Neutralizes harmful free radicals to protect blood vessels and tissues.

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How GNC Niacin 500mg Works

Niacin (vitamin B3) has multiple mechanisms of action that contribute to its heart and vascular benefits:

• Reduces LDL & VLDL cholesterol while lowering triglycerides.

• Increases HDL (good cholesterol) by reducing cholesterol ester transfer protein (CETP) activity.

• Activates HCA2 & HCA3 receptors, lowering fatty acid release and reducing liver triglyceride production.

• Inhibits DGAT2 enzyme, reducing triglyceride synthesis.

• Stimulates nitric oxide & prostaglandins, improving blood flow and lowering blood pressure.

• Breaks down homocysteine, reducing arterial damage risk.

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Key Ingredient

• Niacin (Vitamin B3): 500 mg per vegetarian tablet
  Other ingredients: microcrystalline cellulose, croscarmellose sodium, silicon dioxide, vegetable-sourced stearic acid, and magnesium stearate.

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Niacin Chemical Structure

• Molecular Formula: C₆H₅NO₂

• Molecular Weight: 123.11 g/mol

• Classification: 3-pyridinecarboxylic acid (a water-soluble B-complex vitamin)

• Appearance: White crystalline powder, sparingly soluble in water

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Recommended Dosage & Usage

• Starting Dose: 1 tablet (500 mg) daily, preferably at bedtime after a low-fat snack.

• Adjustment: May increase to 2 tablets (1,000 mg) daily if tolerated.

• Maximum Dose: Do not exceed 2,000 mg daily.

• Special Considerations: Women may respond to lower doses than men.

⚠️ Avoid taking on an empty stomach to minimize flushing and stomach upset.

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Safety Guidelines & Precautions

Before taking GNC Niacin 500mg, consult your doctor if you have:

• Low blood pressure

• Diabetes (niacin may raise blood sugar levels)

• Liver disease or gallbladder problems

• Gout or kidney issues

• Stomach ulcers or intestinal disorders

• Heart disease or glaucoma

Other Warnings:

• Avoid alcohol (increases flushing & side effects).

• May cause dizziness—do not drive until you know how it affects you.

• Inform your doctor if pregnant, breastfeeding, or preparing for surgery.

• Regular monitoring of liver function, uric acid, and blood lipids is recommended.

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Niacin & Drug Interactions

Niacin may interact with many medications, including:

• Blood thinners (anticoagulants): May increase bleeding risk.

• Alpha-blockers: Can enhance blood pressure-lowering effects.

• Bile acid sequestrants (cholestyramine, colestipol): May reduce niacin absorption.

• Diabetes medications (insulin, metformin, glipizide, glyburide): May reduce effectiveness.

• Tetracycline (antibiotic): Avoid taking at the same time as niacin.

• Alcohol: Worsens flushing and stomach irritation.

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Pregnancy & Breastfeeding Considerations

• RDA during pregnancy: 18 mg/day

• RDA during breastfeeding: 17 mg/day

• Normal dietary niacin is safe, but high-dose supplementation (over 2,000 mg/day) should be avoided.

• Niacin passes into breast milk—stick to the lowest effective dose.

Always consult your doctor before use.

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Possible Side Effects of GNC Niacin 500mg

Common side effects include:

• Flushing (warmth, redness, itching)

• Headache & dizziness

• Upset stomach, nausea, or diarrhea

💡 To reduce flushing:

• Take with food (low-fat meal)

• Avoid alcohol & spicy foods

• Start with a lower dose and increase gradually

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Storage Instructions

• Store at room temperature (20°C – 25°C).

• Keep container tightly closed and away from light.

• Do not store in the bathroom or damp areas.

• Keep out of reach of children and pets.

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Reviews & Effectiveness

• No specific customer reviews available for GNC Niacin 500mg.

• General niacin supplements are known to:

  • Lower LDL cholesterol

  • Raise HDL cholesterol

  • Support circulation and heart health

  • Cause flushing and mild digestive discomfort in some users

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Final Verdict

GNC Niacin 500mg is a clinically effective vitamin B3 supplement for supporting cholesterol balance, energy metabolism, and vascular health. While highly effective in raising good cholesterol, it should be taken carefully due to possible side effects and drug interactions.