Description

Topamax (Topiramate) 100 mg – Anticonvulsant & Migraine Prevention

Topamax 100 mg (Topiramate) is a prescription anticonvulsant medication used to treat various types of seizures in adults and children, as well as to prevent migraine headaches in adults. Manufactured in a 60-tablet pack, Topamax offers effective seizure control and migraine prophylaxis when taken under medical supervision.

Key Features of Topamax 100 mg

• Tablet Appearance: Yellow, round, film-coated, imprinted with “OMN” on one side and “100” on the other

• Pack Size: 60 tablets

• Active Ingredient: Topiramate 100 mg

• Medication Class: Anticonvulsant

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Topamax 100 mg Uses

1. Seizure Management

Topamax is approved for the treatment of:

• Partial-onset seizures (with or without secondary generalization)

• Primary generalized tonic-clonic seizures

• Seizures associated with Lennox-Gastaut Syndrome

• For children as young as 2 years, adolescents, and adults

2. Migraine Prevention

• Effective in reducing the frequency of migraine headaches in adults

3. Off-Label Uses

Although not FDA-approved, Topamax is sometimes prescribed for:

• Bipolar disorder

• Anxiety disorders

• Alcohol dependence

• Neuropathic pain and essential tremor

• Weight management (due to appetite suppression)

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Dosage & Administration

• Starting Dose: 25 mg once daily (usually in the evening)

• Titration: Increase by 25–50 mg per week based on response and tolerance

• Epilepsy (Adults): 200–400 mg/day in divided doses

• Migraine Prevention: 100 mg/day in divided doses

• Children (2–9 years): Weight-based dosing (typically 150–400 mg/day)

⚠️ Always follow your doctor’s instructions for dosing and adjustments.

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How Topamax Works (Mechanism of Action)

Topiramate works through multiple mechanisms to reduce seizures and prevent migraines:

• Blocks sodium and calcium channels → decreases neuronal excitability

• Enhances GABA activity → increases inhibitory neurotransmission

• Inhibits glutamate receptors → reduces excitatory signaling

• Carbonic anhydrase inhibition → contributes to anticonvulsant and migraine-preventive effects

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Possible Side Effects

Common side effects may include:

• Drowsiness, dizziness, fatigue

• Tingling in hands/feet

• Memory or concentration difficulties

• Loss of appetite & weight loss

Less common but serious effects:

• Metabolic acidosis

• Kidney stones

• Eye disorders (glaucoma, vision changes)

Seek medical help immediately if severe side effects occur.

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Drug Interactions

Topamax may interact with:

• Certain birth control pills (reducing effectiveness)

• Lithium

• Risperidone

• Other antiepileptic medications

Discuss all medications with your doctor before starting Topamax.

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Storage Instructions

• Store at 15°C–30°C (59°F–86°F) in a tightly-closed container

• Keep away from moisture, heat, and light

• Keep out of reach of children

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Important Safety Notes

• Do not stop Topamax suddenly without medical advice → may cause withdrawal seizures

• If you miss a dose, take it as soon as possible unless close to your next dose (do not double dose)

• Regular check-ups are recommended to monitor long-term side effects

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Summary

Topamax (Topiramate) 100 mg Tablets are widely used for epilepsy treatment and migraine prevention. With its proven effectiveness in seizure control and migraine reduction, Topamax is a trusted therapy prescribed by neurologists worldwide.