Description

Lenvatinib 4mg Capsules Overview

Lenvatinib 4mg Capsules belong to the class of tyrosine kinase inhibitors (TKIs) and are widely prescribed in oncology for the treatment of several advanced cancers. By blocking multiple receptor pathways that promote tumor growth and angiogenesis, Lenvatinib helps slow cancer progression and improve survival outcomes.

Indications (Uses of Lenvatinib 4mg)

Lenvatinib 4mg is prescribed for the treatment of:

• Differentiated Thyroid Cancer (DTC): Used in patients with progressive, locally advanced, or metastatic DTC that is refractory to radioactive iodine (RAI) therapy.

• Hepatocellular Carcinoma (HCC): First-line therapy for advanced or unresectable liver cancer in patients who have not received prior systemic treatment.

• Renal Cell Carcinoma (RCC): Used in combination with other targeted therapies for advanced kidney cancer.

• Endometrial Cancer: In combination with other medications (such as pembrolizumab) for selected patients with advanced or recurrent endometrial cancer.

Recommended Dosage of Lenvatinib 4mg

Dosage varies depending on cancer type and patient body weight:

• Differentiated Thyroid Cancer (DTC): Typically part of a 24mg daily dose, combined with other capsule strengths.

• Hepatocellular Carcinoma (HCC):

  • <60 kg body weight: 8mg daily (two 4mg capsules).

  • ≥60 kg body weight: 12mg daily (three 4mg capsules).

• Endometrial Cancer (with pembrolizumab): Dose adjusted using 4mg and 10mg capsules depending on tolerability.

• Renal Cell Carcinoma (RCC): Given in combination with other drugs such as everolimus.

⚠️ Always follow the exact dosage prescribed by your oncologist, as adjustments may be required based on tolerance and side effects.

Key Benefits of Lenvatinib 4mg Capsules

• Targets multiple cancer growth pathways.

• Helps control tumor progression in advanced cancers.

• Available in multiple capsule strengths for flexible dosing.

• Proven efficacy in thyroid, liver, kidney, and endometrial cancers.

Important Safety Information

Common side effects may include:

• High blood pressure (hypertension)

• Fatigue and weakness

• Nausea, diarrhea, and loss of appetite

• Liver or kidney function abnormalities

Serious side effects can include cardiac issues, blood clots, or gastrointestinal perforation. Regular monitoring of blood pressure, liver function, and kidney function is required during treatment.

Storage Instructions

• Store between 20°C to 25°C (68°F–77°F).

• Keep away from moisture and direct sunlight.

• Store out of reach of children.